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Symbol Name ID |
Rasa3
RAS p21 protein activator 3 MGI:1197013 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | hematopoietic system phenotype |
abnormal megakaryocyte differentiation |
abnormal embryonic hematopoiesis |
enlarged spleen |
increased spleen weight |
abnormal erythropoiesis |
anemia |
decreased bone marrow cell number |
abnormal megakaryocyte morphology |
increased megakaryocyte cell number |
abnormal erythroblast morphology |
decreased erythrocyte cell number |
decreased hematocrit |
increased hemoglobin concentration distribution width |
decreased hemoglobin content |
decreased mean corpuscular hemoglobin |
decreased mean corpuscular hemoglobin concentration |
increased mean corpuscular volume |
increased red blood cell distribution width |
anisocytosis |
poikilocytosis |
polychromatophilia |
thrombocytopenia |
increased mean platelet volume |
decreased B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased T cell number |
decreased leukocyte cell number |
reticulocytosis |
pancytopenia |
increased megakaryocyte-erythroid progenitor cell number |
abnormal spleen morphology |
increased spleen red pulp amount |
pale spleen |
hemolysis |
abnormal platelet physiology |
bone marrow failure |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||
| Rasa3hlb381/Rasa3hlb381 | |||||||||||||||||||||||||||||||||||||||
| Rasa3scat/Rasa3scat | |||||||||||||||||||||||||||||||||||||||
| Rasa3hlb381/? | |||||||||||||||||||||||||||||||||||||||
| Eportm1.1(EGFP/icre)Uk/Epor+ Rasa3tm1.1Llp/Rasa3tm1.1Llp (conditional) |
* | ||||||||||||||||||||||||||||||||||||||
| Rasa3tm1.1Llp/Rasa3tm1.1Llp Tg(Vav1-cre)1Cgp/? (conditional) |
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| Rasa3tm1.1Llp/Rasa3tm1.1Llp Tg(Tek-cre)1Ywa/? (conditional) |
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| Rasa3tm1.1Llp/Rasa3tm1.1Llp Tg(Mx1-cre)1Cgn/? (conditional) |
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| Eportm1.1(EGFP/icre)Uk/Epor+ Rasa3tm1.1Llp/Rasa3tm1.3Llp (conditional) |
* | ||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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